The mandate of the HTS Lab is to provide excellence and innovation in biomolecular screening. The lab has been designed to be highly flexible in order to meet the needs of multiple users wishing to evaluate a variety of assays.

The McMaster HTS Lab is closely associated with the McMaster Antimicrobial Research Centre (ARC) and will primarily be used by McMaster Scientists searching for novel probes to fuel biological and biochemical research initiatives.

The McMaster HTS Lab will also be a unique resource for external scientists in both academia and industry through collaborative and contract research agreements.

Web: High Throughput Screening (HTS) Lab

Infectious diseases continue to be leading health care problems across the globe. The emergence of new infections such as SARS and the return of ‘old’ diseases such as tuberculosis remind us of our susceptibility and vulnerability to pathogens.

The possibility of epidemics of avian flu, bioterror agents and multidrug resistant bacteria are on the radar of health care professionals and the public alike. The phenomena of antibiotic resistance, urbanization, rapid intercontinental traffic, and climate change to name a few, exacerbate the problem.

• Where do infections and epidemics come from and do we know enough to predict their outcome?
• What role does the environment play in disease?
• What do we know about the prevention and spread of infection in the community?

Web: Michael G. DeGroote Institute for Infectious Disease Research (IIDR)

MacBiophotonics is an international imaging facility dedicated to live cell analysis with a large variety of expert systems and techniques. The Facility is available for use by internal, external, and external-academic researchers on a user cost basis.

Web: MacBiophotonics

Established in 2006, the SCCRIrepresents a unique research facility in Canada. The Institute’s vision and mandate is to explore the underlying cellular and molecular origins that initiate human cancer by employing human stem cells as a model system.

Web: Stem Cell and Cancer Research Institute (SCC-RI)

The mission of the McMaster Immunology Research Centre (MIRC) is to investigate, create and implement approaches utilizing the delivery of genes as therapeutic agents in the treatment of human and animal disease. This entails basic investigations to target gene product involvement, creation of vector systems for appropriate delivery of therapeutic genes and rapid translation of promising medicines to the clinical setting.

The Centre is focused on developing novel cures for cancer, inflammatory diseases and infectious diseases using state-of-the-art gene transfer technology coupled with the most recent information derived from the application of genomics.

Web: MIRC Facility

The Farncombe Family Digestive Health Research Institute is an integrated group of clinical and basic scientists dedicated to understanding the impact of digestive health and nutrition on disease across the life span.

The Institute is focused on developing new strategies for diagnosis, treatment and prevention of intestinal diseases such as Crohn’s disease and ulcerative colitis, which will have global benefits. However, the focus of research in the Institute is not limited to digestive diseases; rather, it includes diseases of many other organ systems that may be caused and/or profoundly influenced by digestive health and nutrition.

Web: Farncombe Family Digestive Health Research Institute

The mission of the Centre for Functional Genomics is to develop new technologies and to exploit recent advances in gene expression profiling, bioinformatics and proteomics to discover gene function. This knowledge will be integrated into the investigation of genetic pathways that regulate organismal development and physiology.

Web: CFG Facility

The Centre for Microbial Chemical Biology provides easy access to expertise and equipment necessary for chemical biology research. Expert staff are on hand to maintain the equipment and offer training and assistance for all users. Alternatively, CMCB staff members are available to assist with designing and completing individual experiments and projects for researchers.

The CMCB features six core labs that enable chemical biology research to be conducted in one central location. We provide the capabilities necessary for cell culture, assay development, high throughput screening, small molecule synthesis, natural product isolations, molecule identification for drug discovery and basic research applications.<br>

Web:  Centre for Microbial Chemical Biology (CMCB)