Karun Singh, PhD
Karun Singh, PhD Part-Time Member
Associate Professor (part-time), Department of Biochemistry and Biomedical Sciences, McMaster University
Associate Professor, Department of Ophthalmology & Vision Sciences, University of Toronto
Email: karun.singh@uhnresearch.ca
Visit Karun Singh's Homepage

Research

Our primary research objective is to understand the pathological mechanisms of psychiatric disorders including schizophrenia and autism spectrum disorders. Neuropsychiatric diseases including autism, schizophrenia and bipolar disorder are a major problem in our society as patients have few successful treatment options. One of the reasons is because scientists do not understand the pathogenic mechanisms of these diverse diseases, which makes discovering new drugs for treatment very difficult. Interestingly, neuropsychiatric illnesses tend to run in families, which means there is a genetic basis for these diseases. However only recently have we started to discover the genes that are responsible for increasing risk of disease. Furthermore, there is a lack of model organizms (eg. mouse models) that can faithfully recapitulate the genetic diversity and heterogeneity of these brain disorders.
Sara Andres, PhD
Sara Andres, PhD Faculty
Assistant Professor, Department of Biochemistry and Biomedical Sciences
CLINTON CAMPBELL, MD, PhD, FRCPC
CLINTON CAMPBELL, MD, PhD, FRCPC Associate Member
Assistant Professor, Pathology and Molecular Medicine, Department of Biochemistry and Biomedical Sciences
MANALI MUKHERJEE, PhD
MANALI MUKHERJEE, PhD Associate Member
Assistant Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
JON STOKES, PhD
JON STOKES, PhD Faculty
Department of Biochemistry and Biomedical Sciences
Stephanie Atkinson, PhD
Stephanie Atkinson, PhD Associate Member
Professor, Department of Pediatrics, Department of Biochemistry and Biomedical Sciences
TOBIAS BERG, MD, PHD
TOBIAS BERG, MD, PHD Associate Member
Associate Professor, Department of Oncology, Department of Biochemistry and Biomedical Sciences
Paul Berti, PhD
Paul Berti, PhD Joint Member
Professor, Department of Chemistry, Department of Biochemistry and Biomedical Sciences
Mick Bhatia, PhD
Mick Bhatia, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences, Canada Research Chair
Russell Bishop, PhD
Russell Bishop, PhD Faculty
Associate Professor, Department of Biochemistry and Biomedical Sciences
Jonathan Bramson, PhD
Jonathan Bramson, PhD Associate Member
Professor, Department of Pathology and Molecular Medicine, Department of Biochemistry and Biomedical Sciences
John Brennan, PhD
John Brennan, PhD Associate Member
Professor, Department of Chemistry, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Eric D. Brown, PhD
Eric D. Brown, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair in Chemical Biology
Lori Burrows, PhD
Lori Burrows, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences,
Joint Member, Department of Pathology & Molecular Medicine,
Acting Director of IIDR
Brian Coombes, PhD
Brian Coombes, PhD Faculty
Professor and Chair, Department of Biochemistry and Biomedical Sciences, Canada Research Chair
Marie Elliot, PhD
Marie Elliot, PhD Associate Member
Professor, Department of Biology, Department of Biochemistry and Biomedical Sciences
Cecile Fradin, PhD
Cecile Fradin, PhD Joint Member
Professor, Department of Physics and Astronomy, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Radhey S. Gupta, PhD
Radhey S. Gupta, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences
Thomas Hawke, PhD
Thomas Hawke, PhD Associate Member
Professor, Department of Pathology and Molecular Medicine, Department of Biochemistry and Biomedical Sciences
Paul G. Higgs, PhD
Paul G. Higgs, PhD Joint Member
Professor, Department of Physics and Astronomy, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Stephen Hill, PhD
Stephen Hill, PhD Associate Member
Associate Professor, Department of Pathology and Molecular Medicine, Department of Biochemistry and Biomedical Sciences
Alison Holloway, PHD
Alison Holloway, PHD Associate Member
Associate Professor, Department of Obstetrics and Gynecology, Department of Biochemistry and Biomedical Sciences
Kristin Hope, PhD
Kristin Hope, PhD Part-Time Member
Associate Professor (part-time) Department of Biochemistry; Associate Professor, University of Toronto
Alexander Hynes, PhD

Alexander Hynes, PhD
 Associate Member
Assistant Professor, Department of Medicine,
 Department of Biochemistry and Biomedical Sciences
CHARU KAUSHIC, PhD
CHARU KAUSHIC, PhD Associate Member
Professor, Department of Pathology and Molecular Medicine
, Department of Biochemistry and Biomedical Sciences
Mark Larché, PhD
Mark Larché, PhD Associate Member
Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Yingfu Li, PhD
Yingfu Li, PhD Joint Member
Professor, Department of Chemistry,
Department of Biochemistry and Biomedical Sciences,
Acting Director BDC,
Canada Research Chair in Nucleic Acids Research
Lesley T. MacNeil, PHD
Lesley T. MacNeil, PHD Faculty
Assistant Professor, Department of Biochemistry and Biomedical Sciences,
Farncombe Family Digestive Health Research Institute
Nathan Magarvey, PhD
Nathan Magarvey, PhD Faculty
Associate Professor, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Jakob Magolan, PhD
Jakob Magolan, PhD Faculty
Associate Professor, Department f oBiochemistry and Biomedical Sciences,
Canada Research Chair
Andrew McArthur, PhD
Andrew McArthur, PhD Faculty
Associate Professor, Department of Biochemistry and Biomedical Sciences, Director, Biomedical
Discovery & Commercialization Program
Giuseppe Melacini, PhD
Giuseppe Melacini, PhD Joint Member
Professor, Department of Chemistry, Department of Biochemistry and Biomedical Sciences
Matthew Miller, PhD
Matthew Miller, PhD Faculty
Associate Professor, Department of Biochemistry and Biomedical Sciences, Associate Chair & Assistant Dean, Biochemistry Graduate Program
Karen Mossman, PhD
Karen Mossman, PhD Associate Member
Associate Vice-President (Research), Professor, Department of Pathology and Molecular Biology, Department of Biochemistry and Biomedical Sciences
Ishac Nazy, PhD
Ishac Nazy, PhD Associate Member
Associate Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
GUILLAUME PARÉ, MD, MSc, FRCPC
GUILLAUME PARÉ, MD, MSc, FRCPC Associate Member
Associate Professor, Department of Pathology and Molecular 
Medicine (primary), Department of Clinical Epidemiology and Biostatistics, 
Department of Biochemistry and Biomedical Sciences
Hendrik Poinar, PhD
Hendrik Poinar, PhD Joint Member
Professor, Department of Anthropology, Department of Biochemistry and Biomedical Sciences, Canada Research Chair
Sandeep Raha, PhD
Sandeep Raha, PhD Associate Member
Associate Professor, Department of Pediatrics, Department of Biochemistry and Biomedical Sciences
Jonathan D. Schertzer, PhD
Jonathan D. Schertzer, PhD Faculty
Associate Professor, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Karun Singh, PhD
Karun Singh, PhD Part-Time Member
Associate Professor (part-time) Department of Biochemistry; Associate Professor, University of Toronto
Sheila Singh, MD, PhD, FRCSC
Sheila Singh, MD, PhD, FRCSC Associate Member
Professor, Department of Surgery, Division of Neurosurgery,
Canada Research Chair
Deborah Sloboda, PhD
Deborah Sloboda, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences,
Associate Chair of Research, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Jennifer Stearns, PhD
Jennifer Stearns, PhD Associate Member
Assistant Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
Gregory Steinberg, PhD
Gregory Steinberg, PhD Joint Member
Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences,
Canada Research Chair
Michael Surette, PhD
Michael Surette, PhD Joint Member
Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
Bernardo Trigatti, PhD
Bernardo Trigatti, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences
Ray Truant, PhD
Ray Truant, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences
Jeffrey Weitz, FRCP(C)-FACP
Jeffrey Weitz, FRCP(C)-FACP Associate Member
Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
Director, Thrombosis & Atherosclerosis Research Institute (TaARI),
Canada Research Chair
Geoff Werstuck, PhD
Geoff Werstuck, PhD Joint Member
Professor, Department of Medicine, Department of Biochemistry and Biomedical Sciences
John Whitney, PhD
John Whitney, PhD Faculty
Assistant Professor, Department of Biochemistry and Biomedical Sciences, Michael DeGroote Centre for Learning and Discovery (MDCL)
Gerard D. Wright, PhD
Gerard D. Wright, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences
Director, Michael DeGroote Institute for Infectious Disease Research
Canada Research Chair in Antimicrobial Biochemistry
Daniel S.-C. Yang, PhD
Daniel S.-C. Yang, PhD Faculty
Professor, Department of Biochemistry and Biomedical Sciences